Reference - Detail
| RRC ID | 52856 |
|---|---|
| Author | Shinkai Y, Yoshida MC, Maeda K, Kobata T, Maruyama K, Yodoi J, Yagita H, Okumura K. |
| Title | Molecular cloning and chromosomal assignment of a human perforin (PFP) gene. |
| Journal | Immunogenetics |
| Abstract |
Human perforin cDNA was isolated and the complete nucleotide sequence of the gene determined. The deduced amino acid sequence of human perforin showed 68.4% similarity to that of mouse perforin. RNA blot analysis of the human perforin gene revealed that the gene product is expressed preferentially in killer-type cells among cell lines tested, and in large granular lymphocytes among the peripheral blood mononuclear cells. In situ hybridization analysis with a human perforin cDNA probe revealed that the human perforin (PFP) gene is located on chromosome 17q11-21. |
| Volume | 30(6) |
| Pages | 452-7 |
| Published | 1989-1-1 |
| DOI | 10.1007/BF02421177 |
| PMID | 2592021 |
| MeSH | Base Sequence Blotting, Northern Chromosome Mapping* Chromosomes, Human, Pair 17 Cloning, Molecular* DNA / isolation & purification Humans Membrane Glycoproteins* Membrane Proteins / genetics* Molecular Sequence Data Perforin Pore Forming Cytotoxic Proteins |
| IF | 2.621 |
| Times Cited | 61 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Wikipedia |
| Total number of mentions | 8 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| DNA material | YT101 (RDB01181). |