論文 - 詳細
| RRC ID | 53125 |
|---|---|
| 著者 | Poliner E, Farré EM, Benning C. |
| タイトル | Advanced genetic tools enable synthetic biology in the oleaginous microalgae Nannochloropsis sp. |
| ジャーナル | Plant Cell Rep |
| Abstract |
Nannochloropsis is a genus of fast-growing microalgae that are regularly used for biotechnology applications. Nannochloropsis species have a high triacylglycerol content and their polar lipids are rich in the omega-3 long-chain polyunsaturated fatty acid, eicosapentaenoic acid. Placed in the heterokont lineage, the Nannochloropsis genus has a complex evolutionary history. Genome sequences are available for several species, and a number of transcriptomic datasets have been produced, making this genus a facile model for comparative genomics. There is a growing interest in Nannochloropsis species as models for the study of microalga lipid metabolism and as a chassis for synthetic biology. Recently, techniques for gene stacking, and targeted gene disruption and repression in the Nannochloropsis genus have been developed. These tools enable gene-specific, mechanistic studies and have already allowed the engineering of improved Nannochloropsis strains with superior growth, or greater bioproduction. |
| 巻・号 | 37(10) |
| ページ | 1383-1399 |
| 公開日 | 2018-10-1 |
| DOI | 10.1007/s00299-018-2270-0 |
| PII | 10.1007/s00299-018-2270-0 |
| PMID | 29511798 |
| MeSH | Carbon / metabolism Drug Resistance, Microbial / genetics Gene Expression Regulation Light Lipid Metabolism / genetics Microalgae / classification Microalgae / genetics* Microalgae / metabolism* Photosynthesis Protein Engineering / methods Stramenopiles / classification Stramenopiles / genetics* Stramenopiles / metabolism Synthetic Biology / methods* Transcriptome |
| IF | 3.825 |
| 引用数 | 21 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 44 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 藻類 | NIES-2145 NIES-2146 |