| RRC ID |
53640
|
| Author |
Suzuki K, Moriguchi K, Yamamoto S.
|
| Title |
Horizontal DNA transfer from bacteria to eukaryotes and a lesson from experimental transfers.
|
| Journal |
Res Microbiol
|
| Abstract |
Horizontal gene transfer (HGT) is widespread among bacteria and plays a key role in genome dynamics. HGT is much less common in eukaryotes, but is being reported with increasing frequency in eukaryotes. The mechanism as to how eukaryotes acquired genes from distantly related organisms remains obscure yet. This paper cites examples of bacteria-derived genes found in eukaryotic organisms, and then describes experimental DNA transports to eukaryotes by bacterial type 4 secretion systems in optimized conditions. The mechanisms of the latter are efficient, quite reproducible in vitro and predictable, and thereby would provide insight into natural HGT and to the development of new research tools.
|
| Volume |
166(10)
|
| Pages |
753-63
|
| Published |
2015-12-1
|
| DOI |
10.1016/j.resmic.2015.08.001
|
| PII |
S0923-2508(15)00130-8
|
| PMID |
26291765
|
| MeSH |
Animals
Bacteria / genetics*
DNA, Bacterial / genetics
Eukaryota / genetics*
Evolution, Molecular
Gene Transfer Techniques
Gene Transfer, Horizontal*
Genes, Bacterial*
Phylogeny
Type IV Secretion Systems / genetics
Type IV Secretion Systems / metabolism
|
| IF |
3.217
|
| Times Cited |
4
|
| Resource |
| Prokaryotes E. coli |
|
