Reference - Detail
| RRC ID | 55041 |
|---|---|
| Author | Chumakov I, Rigault P, Guillou S, Ougen P, Billaut A, Guasconi G, Gervy P, LeGall I, Soularue P, Grinas L. |
| Title | Continuum of overlapping clones spanning the entire human chromosome 21q. |
| Journal | Nature |
| Abstract |
A continuous array of overlapping clones covering the entire human chromosome 21q was constructed from human yeast artificial chromosome libraries using sequence-tagged sites as landmarks specifically detected by polymerase chain reaction. The yeast artificial chromosome contiguous unit starts with pericentromeric and ends with subtelomeric loci of 21q. The resulting order of sequence-tagged sites is consistent with other physical and genetic mapping data. This set of overlapping clones will promote our knowledge of the structure of this chromosome and the function of its genes. |
| Volume | 359(6394) |
| Pages | 380-7 |
| Published | 1992-10-1 |
| DOI | 10.1038/359380a0 |
| PMID | 1406950 |
| MeSH | Chromosome Mapping / methods* Chromosomes, Fungal Chromosomes, Human, Pair 21* Cloning, Molecular Gene Library Genetic Markers Genome, Human* Humans Polymerase Chain Reaction Sequence Tagged Sites |
| IF | 43.07 |
| Times Cited | 481 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 28 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| DNA material | CEPH MEGA YAC clone (RDB04215) |