論文 - 詳細
RRC ID | 56265 |
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著者 | Hara S, Hara Y, Arai MA, Kusuya Y, Takahashi H, Yaguchi T, Ishibashi M. |
タイトル | Isolation of Nabscessin C from Nocardia abscessus IFM 10029T and a Study on Biosynthetic Pathway for Nabscessins. |
ジャーナル | Chem Pharm Bull (Tokyo) |
Abstract |
A new aminocyclitol derivative, designated nabscessin C (1), was isolated from Nocardia abscessus IFM 10029T. Nabcessin C is an isomer of nabscessins A (2) and B (3) with different positioning of the acyl group. Absolute configuration of nabscessin A was determined by conversion into the 2-deoxy-scyllo-inosamine pentaacetyl derivative (4) by hydrolysis and acetylation of 2. The biosynthetic pathway of nabscessins is proposed based on gene expression analysis. |
巻・号 | 66(10) |
ページ | 976-982 |
公開日 | 2018-1-1 |
DOI | 10.1248/cpb.c18-00430 |
PMID | 30270243 |
MeSH | Acetylation Animals Cell Line Cell Proliferation Cyclitols / chemistry Cyclitols / isolation & purification Cyclitols / metabolism* Hydrolysis Mice Molecular Structure Nocardia asteroides / chemistry* Nocardia asteroides / metabolism Seeds / chemistry Seeds / metabolism |
IF | 1.405 |
引用数 | 1 |
リソース情報 | |
病原真核微生物 | 病原放線菌: IFM 10029 |