論文 - 詳細
| RRC ID | 56632 |
|---|---|
| 著者 | Hashimoto Y, Ueda M, Kohiga Y, Imura K, Hontsu S. |
| タイトル | Application of fluoridated hydroxyapatite thin film coatings using KrF pulsed laser deposition. |
| ジャーナル | Dent Mater J |
| Abstract |
Fluoridated hydroxyapatite (FHA) was investigated for application as an implant coating for titanium bone substitute materials in dental implants. A KrF pulsed excimer deposition technique was used for film preparation on a titanium plate. The compacts were ablated by laser irradiation at an energy density of 1 J/cm2 on an area 1×1 mm2 with the substrate at room temparature. Energydispersive spectrometric analysis of the FHA film revealed peaks of fluorine in addition to calcium and phosphorus. X-ray diffraction revealed the presence of crystalline FHA on the FHA film after a 10 h post annealing treatment at 450°C. The FHA film coating exhibited significant dissolution resistance to sodium phosphate buffer for up to 21 days, and favorable cell attachment of human mesenchymal stem cells compared with HA film. The results of this study suggest that FHA coatings are suitable for real-world implantation applications. |
| 巻・号 | 37(3) |
| ページ | 408-413 |
| 公開日 | 2018-6-8 |
| DOI | 10.4012/dmj.2017-122 |
| PMID | 29279546 |
| MeSH | Bone Substitutes / chemistry* Cells, Cultured Coated Materials, Biocompatible / chemistry Dental Implants* Dental Materials / chemistry Humans Hydroxyapatites In Vitro Techniques Lasers* Materials Testing Mesenchymal Stem Cells / drug effects Spectrometry, X-Ray Emission Surface Properties Titanium / chemistry X-Ray Diffraction |
| IF | 1.424 |
| 引用数 | 2 |
| リソース情報 | |
| ヒト・動物細胞 | Human mesenchymal stem cells |