論文 - 詳細
| RRC ID | 56917 |
|---|---|
| 著者 | Ishii M, Nishida S, Kataoka K, Nishiyama Y, Abe S, Sekimizu K. |
| タイトル | Lactic acid bacteria of the Leuconostoc genus with high innate immunity-stimulating activity. |
| ジャーナル | Drug Discov Ther |
| Abstract |
We screened lactic acid bacteria that exhibited high innate immunity-stimulating activity by monitoring muscle contraction activity in silkworms. Heat-treated fractions of lactic acid bacteria, Leuconostoc carnosum #7-2, Leuconostoc gelidum #4-2, and Leuconostoc mesenteroides 8/11-3, had high (250-460 units/mg) innate immunity-stimulating activity. These lactic acid bacteria proliferated in milk to concentrations of 1 × 106 colony forming unit/mL. The present findings suggest that the silkworm muscle contraction assay is useful for screening lactic acid bacteria with high innate immunity-stimulating activity, and that the assay can be used for the production of fermented foods made from milk. |
| 巻・号 | 11(1) |
| ページ | 25-29 |
| 公開日 | 2017-3-22 |
| DOI | 10.5582/ddt.2016.01078 |
| PMID | 28202882 |
| MeSH | Adjuvants, Immunologic / pharmacology* Animals Bombyx Immunity, Innate* Leuconostoc / isolation & purification Leuconostoc / physiology* Milk / microbiology |
| 引用数 | 4 |
| オルトメトリクス指標 |
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 3 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
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| カイコ | |