RRC ID 57310
Author Tomita S, Sue M, Kajikawa A, Igimi S, Shinohara H, Yokota K.
Title Detoxification process of tolaasins, lipodepsipeptides, by Microbacterium sp. K3-5.
Journal Biosci Biotechnol Biochem
Abstract Tolaasins are antimicrobial lipodepsipeptides. Here, we report the tolaasins-detoxifying properties of Microbacterium sp. K3-5 (K3-5). The detoxification of tolaasins by K3-5 was performed by hydrolyzation of cyclic structure of tolaasins depending on the tolaasin-K3-5 cell interaction. Our data suggest that the cyclic structure of tolaasins is critical for its interaction to target cells.
Volume 82(8)
Pages 1455-1458
Published 2018-8-1
DOI 10.1080/09168451.2018.1460575
PMID 29658402
MeSH Actinobacteria / metabolism* Chromatography, Liquid Depsipeptides / chemistry Depsipeptides / metabolism* Inactivation, Metabolic* Lipopeptides / chemistry Lipopeptides / metabolism* Peptides, Cyclic / chemistry Peptides, Cyclic / metabolism Protein Conformation Spectrometry, Mass, Electrospray Ionization
IF 1.297
Times Cited 1
General Microbes JCM 1465