RRC ID 57514
Author Kitou Y, Nakajima Y, Maeda K, Jin Q, Nishiuchi T, Kanamaru K, Kobayashi T, Kimura M.
Title Re-examination of genetic and nutritional factors related to trichothecene biosynthesis in Fusarium graminearum.
Journal Biosci Biotechnol Biochem
Abstract Disruption of two Fusarium genes that negatively regulate trichothecene biosynthesis was reported to cause a drastic increase in trichothecene production. However, careful inspection of these genes revealed that neither was significantly related to trichothecene production. Agmatine medium maintained the expression of trichothecene genes at significant levels, resulting in a 2-3-fold increase in the final yield, as compared to glutamine medium.
Volume 80(2)
Pages 414-7
Published 2016-1-1
DOI 10.1080/09168451.2015.1088374
PMID 26413981
MeSH Agmatine / metabolism Agmatine / pharmacology Culture Media / pharmacology Fungal Proteins / genetics* Fungal Proteins / metabolism Fusarium / drug effects Fusarium / genetics* Fusarium / metabolism Gene Deletion Gene Expression Regulation, Fungal* Glutamine / metabolism Glutamine / pharmacology Transcription Factors / genetics* Transcription Factors / metabolism Transcription, Genetic Trichothecenes / biosynthesis* Trichothecenes / genetics
IF 1.297
Times Cited 1
General Microbes JCM 9873