論文 - 詳細
| RRC ID | 57830 |
|---|---|
| 著者 | Koyama S, Narita E, Suzuki Y, Shiina T, Taki M, Shinohara N, Miyakoshi J. |
| タイトル | Long-term exposure to a 40-GHz electromagnetic field does not affect genotoxicity or heat shock protein expression in HCE-T or SRA01/04 cells. |
| ジャーナル | J Radiat Res |
| Abstract |
Millimeter waves are used in various fields, and the risks of this wavelength range for human health must be carefully evaluated. In this study, we investigated the effects of millimeter waves on genotoxicity and heat shock protein expression in human corneal epithelial (HCE-T) and human lens epithelial (SRA01/04) cells. We exposed the cells to 40-GHz millimeter waves at 1 mW/cm2 for 24 h. We observed no statistically significant increase in the micronucleus (MN) frequency or the level of DNA strand breaks in cells exposed to 40-GHz millimeter waves relative to sham-exposed and incubator controls. Heat shock protein (Hsp) expression also exhibited no statistically significant response to the 40-GHz exposure. These results indicate that exposure to 40 GHz millimeter waves under these conditions has little or no effect on MN formation, DNA strand breaks, or Hsp expression in HCE-T or SRA01/04 cells. |
| 巻・号 | 60(4) |
| ページ | 417-423 |
| 公開日 | 2019-7-1 |
| DOI | 10.1093/jrr/rrz017 |
| PII | 5518566 |
| PMID | 31197350 |
| PMC | PMC6640906 |
| MeSH | Cell Line Comet Assay Cornea / cytology* DNA Damage Electromagnetic Fields* Epithelial Cells / cytology* Gene Expression Regulation Heat-Shock Proteins / metabolism* Humans Micronucleus Tests |
| IF | 2.014 |
| 引用数 | 1 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 12 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | HCE-T(RCB2280) SRA 01/04(RCB1591) |