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  • Search Condition : Filter (MeSH = DNA Damage)
Species Resource Title
DNA material tFucci(CA)2/pCSII-EF (RDB15446) Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage.
DNA material CS-RfA-ETBsd (RDB07917) UV-induced activation of ATR is mediated by UHRF2.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) DNA damage-induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation.
Mice RBRC00806 Endonucleosis mediates internalization of cytoplasm into the nucleus.
C.elegans tm2482 The unfolded protein response of the endoplasmic reticulum protects Caenorhabditis elegans against DNA damage caused by stalled replication forks.
C.elegans tm3886 Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues.
C.elegans tm5218 , tm5124 , tm51240 Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53.
C.elegans tm4525 , tm4919 ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription.
Medaka STII A rad50 germline mutation induces tumorigenesis and ataxia-telangiectasia phenotype in a transparent medaka model.
Human and Animal Cells COLO-320(RCB1193) Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer.
Prokaryotes E. coli Keio collection Identification of a novel DNA repair inhibitor using an in silico driven approach shows effective combinatorial activity with genotoxic agents against multidrug‐resistant Escherichia coli
Prokaryotes E. coli Keio collection Developing novel antimicrobials by combining cancer chemotherapeutics with bacterial DNA repair inhibitors
Prokaryotes E. coli JW4019-KC Identification of the target and mode of action for the prokaryotic nucleotide excision repair inhibitor ATBC
Human and Animal Cells A549(RCB0098) , HeLa Discovery of novel DNA-damaging agents through phenotypic screening for DNA double-strand break.
Human and Animal Cells 201B7(HPS0063) Fanconi anemia and Aldehyde Degradation Deficiency Syndrome: Metabolism and DNA repair protect the genome and hematopoiesis from endogenous DNA damage.
Human and Animal Cells MC3T3-E1(RCB1126) Essential Amino Acid Starvation-Induced Oxidative Stress Causes DNA Damage and Apoptosis in Murine Osteoblast-like Cells.
Human and Animal Cells ACC-MESO-4(RCB2293) , Y-MESO-14(RCB5668) POLD1 Is Required for Cell Cycle Progression by Overcoming DNA Damage in Malignant Pleural Mesothelioma.
DNA material CSIV-TRE-RfA-UbC-KT (RDB12878) The ribonuclease domain function is dispensable for SLFN11 to mediate cell fate decision during replication stress response.
Human and Animal Cells MKN45(RCB1001) Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line.
C.elegans tm1473 , tm1145 , tm1125 Caenorhabditis elegans NHR-14/HNF4α regulates DNA damage-induced apoptosis through cooperating with cep-1/p53.