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Species Resource Title
C.elegans tm3886 PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB-RNAPII complex.
C.elegans tm1937 , tm2026 , tm1145 Damage-induced phosphorylation of BRC-1/BRD-1 in meiosis preserves germline integrity.
Drosophila DGRC#122087 Mutational analysis of the Drosophila CMG helicase reveals relationships among chromosome integrity and the maintenance of spindle and centrosome structure.
Yeast PolySUMOylation of PCNA and Rad52 restricts centromeric recombination in fission yeast.
DNA material pDUAL-YFH1 (RDB06191) , SPYFH38F02 (SPW095322) , SpYFH35F02 (SPW094122) Dbl2 interacts with helicases and an endonuclease to maintain the integrity of repetitive regions.
Human and Animal Cells TIG-3(RCB4468) , MRC-5(RCB0218) Ionizing radiation triggers the release of mitochondrial DNA into the cytosol as a signal of mitochondrial damage.
C.elegans tm1298 , tm2026 , tm2134 , tm432 , tm3081 FAN1-mediated translesion synthesis and POLQ/HELQ-mediated end joining generate interstrand crosslink-induced mutations.
Drosophila Retromer promotes the lysosomal turnover of mtDNA.
Human and Animal Cells NB1RGB(RCB0222) , 201B7(HPS0063) Dimethyl Sulfoxide Attenuates Ionizing Radiation-induced Centrosome Overduplication and Multipolar Cell Division in Human Induced Pluripotent Stem Cells.
Human and Animal Cells HeLa/Fucci(SA)5#16(RCB4917) In vitro and in silico study of biological effects on cancer cells in the presence of metallic materials during radiotherapy.
DNA material tFucci(CA)2/pCSII-EF (RDB15446) Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage.
DNA material CS-RfA-ETBsd (RDB07917) UV-induced activation of ATR is mediated by UHRF2.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) DNA damage-induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation.
Mice RBRC00806 Endonucleosis mediates internalization of cytoplasm into the nucleus.
C.elegans tm2482 The unfolded protein response of the endoplasmic reticulum protects Caenorhabditis elegans against DNA damage caused by stalled replication forks.
C.elegans tm3886 Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues.
C.elegans tm5218 , tm5124 , tm51240 Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53.
C.elegans tm4525 , tm4919 ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription.
Medaka STII A rad50 germline mutation induces tumorigenesis and ataxia-telangiectasia phenotype in a transparent medaka model.
Human and Animal Cells COLO-320(RCB1193) Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer.