論文 - 詳細
| RRC ID | 58760 |
|---|---|
| 著者 | Endou M, Yoshida K, Hirota M, Nakajima C, Sakaguchi A, Komatsubara N, Kurihara Y. |
| タイトル | Coxfa4l3, a novel mitochondrial electron transport chain Complex 4 subunit protein, switches from Coxfa4 during spermatogenesis. |
| ジャーナル | Mitochondrion |
| Abstract |
We identified Coxfa4l3, previously called C15orf48 or Nmes1, as a novel accessory protein of Complex IV of the mitochondrial electron transport chain (ETC). Amino acid sequence comparison, the intracellular localization and the protein expression data showed that the protein is the third isoform of Coxfa4 and the expression of Coxfa4 and Coxfa4l3 proteins during spermatogenesis showed a mutually exclusive pattern, implying that Coxfa4 replaces Coxfa4l3 in Complex IV after meiosis. These results may provide some insight into the unique mechanism of ATP production in late spermatogenesis. |
| 巻・号 | 52 |
| ページ | 1-7 |
| 公開日 | 2020-5-1 |
| DOI | 10.1016/j.mito.2020.02.003 |
| PII | S1567-7249(19)30106-0 |
| PMID | 32045714 |
| MeSH | Animals Cell Line Electron Transport Complex IV / genetics* Electron Transport Complex IV / metabolism HEK293 Cells HeLa Cells Humans Male Mice Nuclear Proteins / metabolism* Organ Specificity Proteomics Spermatogenesis* |
| IF | 3.992 |
| 引用数 | 0 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | SP2/0-Ag14(RCB0209) |