Reference - Detail
|Author||Hu CB, Malaphan W, Zendo T, Nakayama J, Sonomoto K.|
|Title||Enterocin X, a novel two-peptide bacteriocin from Enterococcus faecium KU-B5, has an antibacterial spectrum entirely different from those of its component peptides.|
|Journal||Appl Environ Microbiol|
Enterocin X, composed of two antibacterial peptides (Xalpha and Xbeta), is a novel class IIb bacteriocin from Enterococcus faecium KU-B5. When combined, Xalpha and Xbeta display variably enhanced or reduced antibacterial activity toward a panel of indicators compared to each peptide individually. In E. faecium strains that produce enterocins A and B, such as KU-B5, only one additional bacteriocin had previously been known.
|MeSH||Amino Acid Sequence Anti-Bacterial Agents* / chemistry Anti-Bacterial Agents* / metabolism Anti-Bacterial Agents* / pharmacology Bacteria / drug effects Bacteriocins / biosynthesis Bacteriocins / chemistry Bacteriocins / genetics Bacteriocins / metabolism Bacteriocins / pharmacology* Base Sequence Bridged-Ring Compounds / chemistry Bridged-Ring Compounds / metabolism Bridged-Ring Compounds / pharmacology Drug Antagonism Drug Synergism Enterococcus faecium / genetics Enterococcus faecium / growth & development Enterococcus faecium / metabolism Microbial Sensitivity Tests Molecular Sequence Data Peptides / chemistry Peptides / metabolism Peptides / pharmacology* Sequence Analysis, DNA|
|WOS Category||BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY|
|General Microbes||JCM 2504 JCM 5804 JCM 5803 JCM 1157 JCM 5707 JCM 2152 JCM 2504 JCM 2257 JCM 1465|