論文 - 詳細
| RRC ID | 60355 |
|---|---|
| 著者 | Kokubo T, Komano Y, Tsuji R, Fujiwara D, Fujii T, Kanauchi O. |
| タイトル | The Effects of Plasmacytoid Dendritic Cell-Stimulative Lactic Acid Bacteria, Lactococcus lactis Strain Plasma, on Exercise-Induced Fatigue and Recovery via Immunomodulatory Action. |
| ジャーナル | Int J Sport Nutr Exerc Metab |
| Abstract |
The unique lactic acid bacteria, Lactococcus lactis strain plasma (LC-Plasma), stimulates plasmacytoid dendritic cells, which play an important role in viral infection. The authors previously reported that LC-Plasma reduced the number of days athletes experienced cold-like symptoms and fatigue feelings after high-intensity exercise training; however, the mechanism was unclear. In this study, the authors investigated the effect of LC-Plasma on recovery from physical damage after single exercise on a treadmill in BALB/c mice model. Oral administration of LC-Plasma (AIN-93G + 0.029% LC-Plasma) for 4 weeks significantly improved the locomotor reduction after treadmill exercise. This effect was not detected in mice receiving Lactobacillus rhamnosus GG, representative probiotics strain. LC-Plasma also improved voluntary locomotor activity after exercise. Blood and muscle sample analysis indicated that LC-Plasma affects plasmacytoid dendritic cell activation, which, in turn, attenuates muscle degenerative genes and the concentration of fatigue-controlled cytokine transforming growth factor-β. |
| 巻・号 | 29(4) |
| ページ | 354–358 |
| 公開日 | 2019-7-1 |
| DOI | 10.1123/ijsnem.2018-0377 |
| PMID | 31034253 |
| MeSH | Administration, Oral Animals Dendritic Cells / cytology* Dendritic Cells / microbiology Fatigue* Lactobacillales / physiology Lactococcus lactis / physiology* Mice, Inbred BALB C Motor Activity Muscle, Skeletal / physiology* Physical Conditioning, Animal / physiology* Probiotics Transforming Growth Factor beta1 / blood |
| IF | 3.884 |
| 引用数 | 1 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM5805 |