RRC ID 610
Author Yan Y, Kohli A, Koffas MA.
Title Biosynthesis of natural flavanones in Saccharomyces cerevisiae.
Journal Appl. Environ. Microbiol.
Abstract A four-step flavanone biosynthetic pathway was constructed and introduced into Saccharomyces cerevisiae. The recombinant yeast strain was fed with phenylpropanoid acids and produced the flavanones naringenin and pinocembrin 62 and 22 times more efficiently compared to previously reported recombinant prokaryotic strains. Microbial biosynthesis of the flavanone eriodictyol was also achieved.
Volume 71(9)
Pages 5610-3
Published 2005-9
DOI 10.1128/AEM.71.9.5610-5613.2005
PII 71/9/5610
PMID 16151160
PMC PMC1214632
MeSH Flavanones / biosynthesis* Industrial Microbiology / methods Multigene Family* Phenylpropionates / metabolism Plant Proteins / genetics* Plant Proteins / metabolism Recombinant Proteins / genetics Recombinant Proteins / metabolism* Saccharomyces cerevisiae / genetics Saccharomyces cerevisiae / growth & development Saccharomyces cerevisiae / metabolism*
IF 3.633
Times Cited 95
WOS Category BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY
Resource
Arabidopsis / Cultured plant cells, genes pda03082