Reference - Detail
| RRC ID | 6123 |
|---|---|
| Author | Futahashi R, Banno Y, Fujiwara H. |
| Title | Caterpillar color patterns are determined by a two-phase melanin gene prepatterning process: new evidence from tan and laccase2. |
| Journal | Evol Dev |
| Abstract |
The larval color patterns in Lepidoptera exhibit splendid diversity, and identifying the genes responsible for pigment distribution is essential to understanding color-pattern evolution. The swallowtail butterfly, Papilio xuthus, is a good candidate for analyzing marking-associated genes because its body markings change dramatically at the final molt. Moreover, the silkworm Bombyx mori is most suitable for identification of lab-generated color mutants because genome information and many color mutants are available. Here, we analyzed the expression pattern of 10 melanin-related genes in P. xuthus, and analyzed whether these genes were responsible for Bombyx larval color mutants. We found that seven genes correlated strongly with the stage-specific larval cuticular markings of P. xuthus, suggesting that, compared with Drosophila, more genes showed marking specificity in lepidopteran larvae. We newly found that the expression of both tan and laccase2 is strongly correlated with the larval black markings in both P. xuthus and B. mori. The results of F2 linkage analysis and mutant analysis strongly suggest that tan is the responsible gene for Bombyx larval color mutant rouge, and that tan is important in emphasizing black markings of lepidopteran larvae. Detailed comparison of temporal and spatial expression patterns showed that larval cuticular markings were regulated at two different phases. Marking-specific expression of oxidizing enzymes preceded the marking-specific expression of melanin synthesis enzymes at mRNA level, which is the reverse of the melanin synthesis step. |
| Volume | 12(2) |
| Pages | 157-67 |
| Published | 2010-1-1 |
| DOI | 10.1111/j.1525-142X.2010.00401.x |
| PII | EDE401 |
| Description | ro(眼紋赤）の原因遺伝子はショウジョウバエのtanのカイコホモログである。i11系統(ro/ro)では、tanのカイコホモログのエクソン２が完全に欠失している。 |
| PMID | 20433456 |
| MeSH | Animals Bombyx / genetics* Bombyx / growth & development Bombyx / metabolism DNA-Binding Proteins / genetics* DNA-Binding Proteins / metabolism Gene Expression Regulation, Developmental* Genes, Insect / physiology* Genetic Linkage In Situ Hybridization Laccase / genetics* Laccase / metabolism Larva / genetics Larva / growth & development Larva / metabolism Melanins / genetics* Melanins / metabolism Skin Pigmentation / genetics* |
| IF | 1.925 |
| Times Cited | 61 |
| WOS Category | GENETICS & HEREDITY EVOLUTIONARY BIOLOGY DEVELOPMENTAL BIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Silkworms | i11 EST database |