RRC ID 61404
著者 Umezawa T, Chen P, Tsutsumi Y, Doi H, Ashida M, Suzuki S, Moriyama K, Hanawa T.
タイトル Calcification of MC3T3-E1 cells on titanium and zirconium.
ジャーナル Dent Mater J
Abstract To confirm similarity of hard tissue compatibility between titanium and zirconium, calcification of MC3T3-E1 cells on titanium and zirconium was evaluated in this study. Mirror-polished titanium (Ti) and zirconium (Zr) disks and zirconium-sputter deposited titanium (Zr/Ti) were employed in this study. The surface of specimens were characterized using scanning electron microscopy and X-ray diffraction. Then, the cellular proliferation, differentiation and calcification of MC3T3-E1 cells on specimens were investigated. The surface of Zr/Ti was much smoother and cleaner than those of Ti and Zr. The proliferation of the cell was the same among three specimens, while the differentiation and calcification on Zr/Ti were faster than those on Ti and Zr. Therefore, Ti and Zr showed the identical hard tissue compatibility according to the evaluation with MC3T3-E1 cells. Sputter deposition may improve cytocompatibility.
巻・号 34(5)
ページ 713-8
公開日 2015-1-1
DOI 10.4012/dmj.2015-018
PMID 26438997
MeSH 3T3 Cells Animals Calcification, Physiologic / drug effects* Cell Differentiation / drug effects Mice Osteogenesis / drug effects Titanium / pharmacology* Zirconium / pharmacology*
IF 1.359
リソース情報
ヒト・動物細胞 MC3T3-E1(RCB1126)