Reference - Detail
| RRC ID | 61448 |
|---|---|
| Author | Warashina T, Umehara K, Miyase T. |
| Title | Constituents from the roots of Taraxacum platycarpum and their effect on proliferation of human skin fibroblasts. |
| Journal | Chem Pharm Bull (Tokyo) |
| Abstract |
A MeOH extract from the roots of Taraxacum platycarpum has shown significant effects on the proliferation of normal human skin fibroblasts. Chemical analysis of the extract resulted in the isolation of 26 compounds, including eight new triterpenes, one new sesquiterpene glycoside, and seventeen known compounds. The structure of each new compound was established using NMR spectroscopy. Some triterpenes had a significant effect on the proliferation of normal human skin fibroblasts. |
| Volume | 60(2) |
| Pages | 205-12 |
| Published | 2012-1-1 |
| DOI | 10.1248/cpb.60.205 |
| PII | JST.JSTAGE/cpb/60.205 |
| PMID | 22293479 |
| MeSH | Cell Proliferation / drug effects Fibroblasts / cytology Fibroblasts / drug effects* Humans Magnetic Resonance Spectroscopy Methanol / chemistry Models, Molecular Molecular Structure Plant Extracts / chemistry Plant Extracts / pharmacology* Plant Roots / chemistry* Skin / chemistry* Skin / cytology Taraxacum / chemistry* Triterpenes / chemistry Triterpenes / pharmacology |
| IF | 1.416 |
| Resource | |
| Human and Animal Cells | NB1RGB(RCB0222) |