RRC ID 64527
著者 Ötvös K, Miskolczi P, Marhavý P, Cruz-Ramírez A, Benková E, Robert S, Bakó L.
タイトル Pickle Recruits Retinoblastoma Related 1 to Control Lateral Root Formation in Arabidopsis.
ジャーナル Int J Mol Sci
Abstract Lateral root (LR) formation is an example of a plant post-embryonic organogenesis event. LRs are issued from non-dividing cells entering consecutive steps of formative divisions, proliferation and elongation. The chromatin remodeling protein PICKLE (PKL) negatively regulates auxin-mediated LR formation through a mechanism that is not yet known. Here we show that PKL interacts with RETINOBLASTOMA-RELATED 1 (RBR1) to repress the LATERAL ORGAN BOUNDARIES-DOMAIN 16 (LBD16) promoter activity. Since LBD16 function is required for the formative division of LR founder cells, repression mediated by the PKL-RBR1 complex negatively regulates formative division and LR formation. Inhibition of LR formation by PKL-RBR1 is counteracted by auxin, indicating that, in addition to auxin-mediated transcriptional responses, the fine-tuned process of LR formation is also controlled at the chromatin level in an auxin-signaling dependent manner.
巻・号 22(8)
公開日 2021-4-8
DOI 10.3390/ijms22083862
PII ijms22083862
PMID 33917959
PMC PMC8068362
MeSH Arabidopsis / physiology* Arabidopsis Proteins / genetics* Arabidopsis Proteins / metabolism* Chromatin Assembly and Disassembly DNA Helicases / metabolism* Gene Expression Regulation, Plant Indoleacetic Acids / metabolism Organogenesis, Plant / genetics* Plant Development / genetics* Plant Roots / physiology* Promoter Regions, Genetic Protein Binding Signal Transduction
IF 4.556
リソース情報
シロイヌナズナ / 植物培養細胞・遺伝子 pda20017