RRC ID |
64527
|
Author |
Ötvös K, Miskolczi P, Marhavý P, Cruz-Ramírez A, Benková E, Robert S, Bakó L.
|
Title |
Pickle Recruits Retinoblastoma Related 1 to Control Lateral Root Formation in Arabidopsis.
|
Journal |
Int J Mol Sci
|
Abstract |
Lateral root (LR) formation is an example of a plant post-embryonic organogenesis event. LRs are issued from non-dividing cells entering consecutive steps of formative divisions, proliferation and elongation. The chromatin remodeling protein PICKLE (PKL) negatively regulates auxin-mediated LR formation through a mechanism that is not yet known. Here we show that PKL interacts with RETINOBLASTOMA-RELATED 1 (RBR1) to repress the LATERAL ORGAN BOUNDARIES-DOMAIN 16 (LBD16) promoter activity. Since LBD16 function is required for the formative division of LR founder cells, repression mediated by the PKL-RBR1 complex negatively regulates formative division and LR formation. Inhibition of LR formation by PKL-RBR1 is counteracted by auxin, indicating that, in addition to auxin-mediated transcriptional responses, the fine-tuned process of LR formation is also controlled at the chromatin level in an auxin-signaling dependent manner.
|
Volume |
22(8)
|
Published |
2021-4-8
|
DOI |
10.3390/ijms22083862
|
PII |
ijms22083862
|
PMID |
33917959
|
PMC |
PMC8068362
|
MeSH |
Arabidopsis / physiology*
Arabidopsis Proteins / genetics*
Arabidopsis Proteins / metabolism*
Chromatin Assembly and Disassembly
DNA Helicases / metabolism*
Gene Expression Regulation, Plant
Indoleacetic Acids / metabolism
Organogenesis, Plant / genetics*
Plant Development / genetics*
Plant Roots / physiology*
Promoter Regions, Genetic
Protein Binding
Signal Transduction
|
IF |
4.556
|
Resource |
Arabidopsis / Cultured plant cells, genes |
pda20017 |