RRC ID 66252
Author Vuong Van Hung Le, Ieuan G. Davies, Christina D. Moon, David Wheeler, Patrick J. Biggs, Jasna Rakonjac
Title Novel 5-Nitrofuran-Activating Reductase in Escherichia coli
Journal Antimicrobial Agents and Chemotherapy
Abstract The global spread of multidrug-resistant enterobacteria warrants new strategies to combat these pathogens. One possible approach is the reconsideration of “old” antimicrobials, which remain effective after decades of use. Synthetic 5-nitrofurans such as furazolidone, nitrofurantoin, and nitrofurazone are such a class of antimicrobial drugs.
Volume 63
Published 2019-11-1
DOI 10.1128/aac.00868-19
PMID 31481448
IF 4.715
Prokaryotes E. coli