RRC ID 66331
Author Hasegawa M, Fujii S, Funato K, Yoshida A, Sambongi Y.
Title Expression of two glutamate decarboxylase genes in Lactobacillus brevis during gamma-aminobutyric acid production with date residue extract.
Journal Biosci Biotechnol Biochem
Abstract Gamma-aminobutyric acid (GABA) is produced by Lactobacillus brevis using date residue fermentation. In this study, the GABA production method was improved, for which L. brevis strain JCM 1059T was the most efficient among the four L. brevis strains examined. This was presumably due to a difference in the expression level of the gene encoding glutamate decarboxylase that catalyzes GABA synthesis.Abbreviation: GABA: gamma-aminobutyric acid.
Volume 84(5)
Pages 1069-1072
Published 2020-5-1
DOI 10.1080/09168451.2020.1714422
PMID 31931681
MeSH Amino Acid Sequence Bacterial Proteins / metabolism Fermentation Gene Expression Regulation, Bacterial Genes, Bacterial / genetics Glutamate Decarboxylase / genetics* Glutamate Decarboxylase / metabolism Hydrogen-Ion Concentration Levilactobacillus brevis / enzymology* Levilactobacillus brevis / genetics* Phoeniceae / chemistry* Plant Extracts / metabolism* RNA, Ribosomal, 16S / genetics Reverse Transcriptase Polymerase Chain Reaction gamma-Aminobutyric Acid / metabolism*
Resource
General Microbes JCM1059 JCM1061 JCM1170 JCM1559