RRC ID 6652
Author Maeda M, Kuwayama H, Yokoyama M, Nishio K, Morio T, Urushihara H, Katoh M, Tanaka Y, Saito T, Ochiai H, Takemoto K, Yasukawa H, Takeuchi I.
Title Developmental changes in the spatial expression of genes involved in myosin function in Dictyostelium.
Journal Dev Biol
Abstract We analyzed the spatial expression patterns of the genes involved in myosin function by in situ hybridization at the tipped aggregate and early culmination stages of Dictyostelium. Myosin heavy chain II mRNA was enriched in the anterior prestalk region of the tipped aggregates, whereas it disappeared from there and began to appear in both upper and lower cups of the early culminants. Similarly, mRNAs for essential light chain, regulatory light chain, myosin light chain kinase A, and myosin heavy chain kinase C were enriched in the prestalk region of the tipped aggregates. However, expression of these genes was distinctively regulated in the early culminants. These findings suggest the existence of mechanisms responsible for the expression of particular genes.
Volume 223(1)
Pages 114-9
Published 2000-7-1
DOI 10.1006/dbio.2000.9736
PII S0012-1606(00)99736-7
PMID 10864465
MeSH Animals Calcium-Calmodulin-Dependent Protein Kinases / biosynthesis Dictyostelium / genetics* Dictyostelium / metabolism* Gene Expression Regulation, Developmental* In Situ Hybridization Myosin Heavy Chains / biosynthesis Myosin Light Chains / biosynthesis Myosin-Light-Chain Kinase / biosynthesis Myosins / biosynthesis* Myosins / chemistry Myosins / physiology Protozoan Proteins RNA, Messenger / metabolism
IF 2.896
Times Cited 19
Cellular slime molds G24038 G01956 G21368 G00347 G00342 G00811 G03235 G23385