論文 - 詳細
| RRC ID | 66714 |
|---|---|
| 著者 | Munoz J, James K, Bottacini F, Van Sinderen D. |
| タイトル | Biochemical analysis of cross-feeding behaviour between two common gut commensals when cultivated on plant-derived arabinogalactan. |
| ジャーナル | Microb Biotechnol |
| Abstract |
In this paper, we reveal and characterize cross-feeding behaviour between the common gut commensal Bacteroides cellulosilyticus (Baccell) and certain bifidobacterial strains, including Bifidobacterium breve UCC2003, when grown on a medium containing Larch Wood Arabinogalactan (LW-AG). We furthermore show that cross-feeding is dependent on the release of β-1,3-galacto-di/trisaccharides (β-1,3-GOS), and identified that the bga gene cluster of B. breve UCC2003 allows β-1,3-GOS metabolism. The product of bgaB is presumed to be responsible for the import of β-1,3-GOS, while the bgaA gene product, a glycoside hydrolase family 2 member, was shown to hydrolyse both β-1,3-galactobiose and β-1,3-galactotriose into galactose monomers. This study advances our understanding of strain-specific syntrophic interactions between two glycan degraders in the human gut in the presence of AG-type dietary polysaccharides. |
| 巻・号 | 13(6) |
| ページ | 1733-1747 |
| 公開日 | 2020-11-1 |
| DOI | 10.1111/1751-7915.13577 |
| PMID | 32385941 |
| PMC | PMC7533333 |
| MeSH | Bacteroides Bifidobacterium / genetics Feeding Behavior Galactans Gastrointestinal Microbiome* Humans |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 12 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM7017 |