RRC ID 67077
Author Inaba H, Yamamoto T, Iwasaki T, Kabir AMR, Kakugo A, Sada K, Matsuura K.
Title Stabilization of microtubules by encapsulation of the GFP using a Tau-derived peptide.
Journal Chem Commun (Camb)
Abstract We constructed GFP-encapsulated microtubules (MTs) using a Tau-derived peptide which binds to their interior. The encapsulation of the GFP dramatically increased the rigidity of MTs, resulting in their enhanced velocity on a kinesin-coated substrate. Moreover, the GFP-encapsulated MTs were significantly more stable than normal MTs.
Volume 55(62)
Pages 9072-9075
Published 2019-8-11
DOI 10.1039/c9cc04345d
PMID 31268098
MeSH Green Fluorescent Proteins / chemistry* Microtubules / chemistry* Models, Molecular Particle Size Peptides / chemistry* Surface Properties tau Proteins / chemistry*
IF 5.996
DNA material pMal-c2X MBP-GFP1-10 (RDB17883)