論文 - 詳細
| RRC ID | 67809 |
|---|---|
| 著者 | Monteiro PR, do Amaral SC, Siqueira AS, Xavier LP, Santos AV. |
| タイトル | Anabaenopeptins: What We Know So Far. |
| ジャーナル | Toxins (Basel) |
| Abstract |
Cyanobacteria are microorganisms with photosynthetic mechanisms capable of colonizing several distinct environments worldwide. They can produce a vast spectrum of bioactive compounds with different properties, resulting in an improved adaptative capacity. Their richness in secondary metabolites is related to their unique and diverse metabolic apparatus, such as Non-Ribosomal Peptide Synthetases (NRPSs). One important class of peptides produced by the non-ribosomal pathway is anabaenopeptins. These cyclic hexapeptides demonstrated inhibitory activity towards phosphatases and proteases, which could be related to their toxicity and adaptiveness against zooplankters and crustaceans. Thus, this review aims to identify key features related to anabaenopeptins, including the diversity of their structure, occurrence, the biosynthetic steps for their production, ecological roles, and biotechnological applications. |
| 巻・号 | 13(8) |
| 公開日 | 2021-7-27 |
| DOI | 10.3390/toxins13080522 |
| PII | toxins13080522 |
| PMID | 34437393 |
| PMC | PMC8402340 |
| MeSH | Animals Ecology Molecular Structure Peptides, Cyclic* / biosynthesis Peptides, Cyclic* / chemistry Peptides, Cyclic* / toxicity Protease Inhibitors / chemistry Protease Inhibitors / metabolism Protease Inhibitors / toxicity |
| IF | 3.531 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | News |
| 各媒体での言及数の合計 | 5 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 藻類 | NIES-81 NIES-204 NIES-595 |