RRC ID 68590
Author Holden JK, Crawford JJ, Noland CL, Schmidt S, Zbieg JR, Lacap JA, Zang R, Miller GM, Zhang Y, Beroza P, Reja R, Lee W, Tom JYK, Fong R, Steffek M, Clausen S, Hagenbeek TJ, Hu T, Zhou Z, Shen HC, Cunningham CN.
Title Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.
Journal Cell Rep
Volume 31(12)
Pages 107809
Published 2020-6-23
DOI 10.1016/j.celrep.2020.107809
PII S2211-1247(20)30790-7
PMID 32579935
MeSH Animals Cell Line Crystallography, X-Ray Humans Lipids / chemistry* Lipoylation Mice Protein Serine-Threonine Kinases / metabolism* Repressor Proteins / metabolism Signal Transduction* / drug effects Small Molecule Libraries / chemistry Small Molecule Libraries / pharmacology* Transcription Factors / agonists Transcription Factors / metabolism* Xenograft Model Antitumor Assays
IF 8.109
Resource
Human and Animal Cells HuH-7(RCB1942)