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  • Search Condition : Filter (MeSH = Xenograft Model Antitumor Assays)
Species Resource
DNA material Ax1w1 (RDB1746) E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer.
DNA material AxCAZ3-F/RGD (RDB02194) , AxCALacZ (RDB01745) , Ax1w1 (RDB01746). E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers.
DNA material pCAcc-Luc+ (RDB02443) Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1.
DNA material hTRAIL/pMKITneo human TRAIL cDNA (RDB02934) Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma.
DNA material AxCAUT (RDB02050) , pAxcwit (RDB03120) Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models.
Mice B6.Cg-Tg(Tec-p210 BCR/ABL1)1Homy(RBRC02339) NADPH oxidases as therapeutic targets in chronic myelogenous leukemia.
DNA material hTRAIL/pMKITneo (RDB02934) YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation.
DNA material Human MDR1 cDNA (RDB01372) Cabozantinib reverses multidrug resistance of human hepatoma HepG2/adr cells by modulating the function of P-glycoprotein.
DNA material CSII-CMV-RfA (RDB04386) , CSII-EF-RfA (RDB04387). A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.
DNA material CSII-CMV-Venus (RDB05553) A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma.
Zebrafish evanescence REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survival.
DNA material pTnT-TUG1 exon1 (RDB15794) , pTnT-TUG1 exon2 (RDB15795) , pTnT-TUG1 exon3 (RDB15796). Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment.
Mice GFP-LC3#53(RBRC00806) ATG4B inhibitors with a benzotropolone core structure block autophagy and augment efficiency of chemotherapy in mice.
DNA material CS-RfA-ETV (RDB08020) , CS-RfA-ETR (RDB08362) , CSII-EF-MCS-IRES2-hKO1 (RDB07915) , CSII-EF-MCS-IRES2-Venus (RDB04384) , CS-RfA-ETBsd (RDB07917) , pENTR4-H1tetOx1 (RDB07916). Genetic regulation of the RUNX transcription factor family has antitumor effects.
DNA material pKM2L-phMK (RDB05514) Molecular engineering and validation of an oncolytic herpes simplex virus type 1 transcriptionally targeted to midkine-positive tumors.
DNA material Ax1 CA gfp (RDB01727) , AxCAEGFP-F/RGD (RDB03010). Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) , CS-CDF-CG-PRE (RDB04379). Functional in vivo optical imaging of tumor angiogenesis, growth, and metastasis prevented by administration of anti-human VEGF antibody in xenograft model of human fibrosarcoma HT1080 cells.
Mice STOCK Tg(Nanog-GFP , Puro)1Yam(RBRC02290) Role of Lefty in the anti tumor activity of human adult liver stem cells.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway.