RRC ID |
69781
|
著者 |
Fujita T, Lin J, Kimishima A, Arai M, Takikawa H, Ogura Y.
|
タイトル |
Synthesis and biological evaluation of cajaninstilbene acid and amorfrutins A-D as cytotoxic agents against human pancreatic carcinoma PANC-1 cells.
|
ジャーナル |
Biosci Biotechnol Biochem
|
Abstract |
A concise synthesis of cajaninstilbene acid was achieved in seven steps from (E)-3,5-dimethoxystilbene in 8.6% overall yield via the Claisen rearrangement of an aryl reverse-prenyl ether as the key step. Cytotoxic activities against human pancreatic carcinoma PANC-1 cells of cajaninstilbene acid and amorfrutins A-D were also evaluated.
|
巻・号 |
86(5)
|
ページ |
590-595
|
公開日 |
2022-4-21
|
DOI |
10.1093/bbb/zbac025
|
PII |
6528368
|
PMID |
35157035
|
MeSH |
Cytotoxins*
Humans
Pancreatic Neoplasms
Salicylates
Stilbenes* / pharmacology
|
IF |
1.516
|
リソース情報 |
ヒト・動物細胞 |
PANC-1(RCB2095) |