論文 - 詳細
| RRC ID | 7002 |
|---|---|
| 著者 | Yamauchi N. |
| タイトル | The pathway of leucine to mevalonate in halophilic archaea: efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in Halobacterium salinarum. |
| ジャーナル | Biosci Biotechnol Biochem |
| Abstract |
The pathway of leucine to mevalonate, which has attracted attention in the study of the biosynthesis of isoprenoid in parasitic protozoa and myxobacterium, was observed in the biosynthesis of the lipid core in halophilic archaea. The involvement of isovaleryl-CoA dehydrogenase was strongly suggested, with stereospecific conversion of the diastereotopic methyl group of leucine to isoprenoidal lipid. |
| 巻・号 | 74(2) |
| ページ | 443-6 |
| 公開日 | 2010-1-1 |
| DOI | 10.1271/bbb.90814 |
| PII | JST.JSTAGE/bbb/90814 |
| PMID | 20139592 |
| MeSH | Halobacteriales / genetics Halobacteriales / metabolism* Halobacterium salinarum / genetics Halobacterium salinarum / metabolism* Isovaleryl-CoA Dehydrogenase / genetics Isovaleryl-CoA Dehydrogenase / metabolism* Leucine / genetics Leucine / metabolism* Lipids / genetics Mevalonic Acid / metabolism* |
| IF | 1.516 |
| 引用数 | 6 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| リソース情報 | |
| 一般微生物 | JCM 9120 |