論文 - 詳細
| RRC ID | 7005 |
|---|---|
| 著者 | Takehara M, Hibino A, Saimura M, Hirohara H. |
| タイトル | High-yield production of short chain length poly(epsilon-L-lysine) consisting of 5-20 residues by Streptomyces aureofaciens, and its antimicrobial activity. |
| ジャーナル | Biotechnol Lett |
| Abstract |
Poly(epsilon-L-lysine) (epsilon-PL) is a naturally-occurring L-lysine homopolymer having antimicrobial activity. A newly-isolated strain of Streptomyces aureofaciens produced a short chain length epsilon-PL consisting of 5-20 residues at the highest production level of 4.5 g l(-1). This epsilon-PL had different spectra in terms of antimicrobial activity from the epsilon-PL that is now used as a food preservative. The high productivity was based on multiple metabolic pathways for L-lysine synthesis, and a great flux from L-lysine to epsilon-PL. The usefulness of this new epsilon-PL and its producing strain was discussed. |
| 巻・号 | 32(9) |
| ページ | 1299-303 |
| 公開日 | 2010-9-1 |
| DOI | 10.1007/s10529-010-0294-9 |
| PMID | 20464451 |
| MeSH | Amino Acids / analysis Anti-Bacterial Agents / biosynthesis* Anti-Bacterial Agents / chemistry Anti-Bacterial Agents / pharmacology* Chromatography, High Pressure Liquid Metabolic Networks and Pathways / genetics Models, Biological Polylysine / biosynthesis* Polylysine / chemistry Polylysine / pharmacology* Streptomyces aureofaciens / metabolism* |
| IF | 1.977 |
| 引用数 | 28 |
| WOS 分野 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY |
| リソース情報 | |
| 一般微生物 | JCM 2788 |