RRC ID 7210
Author Mungall CJ, Gkoutos GV, Smith CL, Haendel MA, Lewis SE, Ashburner M.
Title Integrating phenotype ontologies across multiple species.
Journal Genome Biol.
Abstract Phenotype ontologies are typically constructed to serve the needs of a particular community, such as annotation of genotype-phenotype associations in mouse or human. Here we demonstrate how these ontologies can be improved through assignment of logical definitions using a core ontology of phenotypic qualities and multiple additional ontologies from the Open Biological Ontologies library. We also show how these logical definitions can be used for data integration when combined with a unified multi-species anatomy ontology.
Volume 11(1)
Pages R2
Published 2010-1-8
DOI 10.1186/gb-2010-11-1-r2
PII gb-2010-11-1-r2
PMID 20064205
PMC PMC2847714
MeSH Algorithms Animals Automation Chromosome Mapping / methods* Computational Biology / methods Genome* Genome, Human Genotype Humans Mice Models, Biological Phenotype Software Species Specificity*
IF 14.028
Times Cited 128
WOS Category BIOTECHNOLOGY & APPLIED MICROBIOLOGY GENETICS & HEREDITY
Resource
INFORMATION Oryzabase