論文 - 詳細
| RRC ID | 72383 |
|---|---|
| 著者 | Hamada T, Ui-Tei K, Imaki J, Miyata Y. |
| タイトル | Molecular cloning of SCDGF-B, a novel growth factor homologous to SCDGF/PDGF-C/fallotein. |
| ジャーナル | Biochem Biophys Res Commun |
| Abstract |
Spinal cord-derived growth factor (SCDGF)/platelet-derived growth factor (PDGF)-C/fallotein has a unique two-domain structure, as it contains two regions homologousto CUB and PDGF/vascular endothelial growth factor (VEGF) domains. In this study, we isolateda novel gene homologous to SCDGF/PDGF-C/fallotein, and named SCDGF-B. The culture supernatant of CHO-K1 cells stably transfected with SCDGF-B showed mitogenic activity as SCDGF/PDGF-C/fallotein did. Although SCDGF-B and SCDGF/PDGF-C/fallotein might be the members of the PDGF/VEGF superfamily of growth factors, they were categorized into a new subfamily in addition to PDGF and VEGF subfamilies. |
| 巻・号 | 280(3) |
| ページ | 733-7 |
| 公開日 | 2001-1-26 |
| DOI | 10.1006/bbrc.2000.4187 |
| PII | S0006-291X(00)94187-1 |
| PMID | 11162582 |
| MeSH | Amino Acid Sequence Animals Base Sequence CHO Cells Cloning, Molecular Cricetinae DNA Primers / genetics Humans Lymphokines / chemistry Lymphokines / genetics* Lymphokines / pharmacology Mitogens / pharmacology Molecular Sequence Data Phylogeny Platelet-Derived Growth Factor / chemistry Platelet-Derived Growth Factor / genetics* Platelet-Derived Growth Factor / pharmacology Protein Structure, Tertiary Rats Recombinant Proteins / chemistry Recombinant Proteins / genetics Recombinant Proteins / pharmacology Sequence Homology, Amino Acid Transfection |
| IF | 2.985 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 8 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | CHO-K1(RCB0285) 10T1/2 (RCB0247) |