| RRC ID |
72693
|
| 著者 |
Murakami H, Kakutani N, Kuroyanagi Y, Iwai M, Hori K, Shimojima M, Ohta H.
|
| タイトル |
MYB-like transcription factor NoPSR1 is crucial for membrane lipid remodeling under phosphate starvation in the oleaginous microalga Nannochloropsis oceanica.
|
| ジャーナル |
FEBS Lett
|
| Abstract |
Membrane lipid remodeling under phosphate (Pi) limitation, a process that replaces structural membrane phospholipids with nonphosphorus lipids, is a widely observed adaptive response in plants and algae. Here, we identified the transcription factor phosphorus starvation response 1 (NoPSR1) as an indispensable player for regulating membrane lipid conversion during Pi starvation in the microalga Nannochloropsis oceanica. Knocking out NoPSR1 scarcely perturbed membrane lipid composition under Pi-sufficient conditions but significantly impaired dynamic alteration in membrane lipids during Pi starvation. In contrast, the absence of NoPSR1 led to no obvious change in cell proliferation or storage lipid accumulation under either nutrient-sufficient or Pi-deficient conditions. Our results demonstrate a key factor controlling the membrane lipid profile during the Pi starvation response in N. oceanica.
|
| 巻・号 |
594(20)
|
| ページ |
3384-3394
|
| 公開日 |
2020-10-1
|
| DOI |
10.1002/1873-3468.13902
|
| PMID |
32770739
|
| MeSH |
Algal Proteins / chemistry
Algal Proteins / metabolism*
Amino Acid Sequence
Arabidopsis / metabolism
Gene Expression Regulation
Lipid Metabolism*
Membrane Lipids / metabolism*
Microalgae / genetics
Microalgae / metabolism*
Mutation / genetics
N-Acetylglucosaminyltransferases / metabolism
Phosphates / deficiency*
Protein Domains
Time Factors
Transcription Factors / metabolism*
Transcription, Genetic
|
| IF |
3.057
|
| リソース情報 |
| 藻類 |
NIES-2145 |
