RRC ID 72891
著者 Ali AM, Mackeen MM, Hamid M, Aun QB, Zauyah Y, Azimahtol HL, Kawazu K.
タイトル Cytotoxicity and electron microscopy of cell death induced by goniothalamin.
ジャーナル Planta Med
Abstract The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level, goniothalamin-induced cytotoxicity revealed a necrotic mode of cell death towards MCF-7 cells.
巻・号 63(1)
ページ 81-3
公開日 1997-2-1
DOI 10.1055/s-2006-957611
PMID 9063100
MeSH 3T3 Cells Animals Antineoplastic Agents, Phytogenic / pharmacology* Cell Death / drug effects* Humans Mice Microscopy, Electron Pyrones / pharmacology* Tumor Cells, Cultured
IF 2.687
リソース情報
ヒト・動物細胞 HGC-27(RCB0500) 3T3, mouse fibroblast