論文 - 詳細
| RRC ID | 72891 |
|---|---|
| 著者 | Ali AM, Mackeen MM, Hamid M, Aun QB, Zauyah Y, Azimahtol HL, Kawazu K. |
| タイトル | Cytotoxicity and electron microscopy of cell death induced by goniothalamin. |
| ジャーナル | Planta Med |
| Abstract |
The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level, goniothalamin-induced cytotoxicity revealed a necrotic mode of cell death towards MCF-7 cells. |
| 巻・号 | 63(1) |
| ページ | 81-3 |
| 公開日 | 1997-2-1 |
| DOI | 10.1055/s-2006-957611 |
| PMID | 9063100 |
| MeSH | 3T3 Cells Animals Antineoplastic Agents, Phytogenic / pharmacology* Cell Death / drug effects* Humans Mice Microscopy, Electron Pyrones / pharmacology* Tumor Cells, Cultured |
| IF | 2.687 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 各媒体での言及数の合計 | 0 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | HGC-27(RCB0500) 3T3, mouse fibroblast |