論文 - 詳細
| RRC ID | 74111 |
|---|---|
| 著者 | Katsuma S, Hirota K, Matsuda-Imai N, Fukui T, Muro T, Nishino K, Kosako H, Shoji K, Takanashi H, Fujii T, Arimura SI, Kiuchi T. |
| タイトル | A Wolbachia factor for male killing in lepidopteran insects. |
| ジャーナル | Nat Commun |
| Abstract |
Bacterial symbionts, such as Wolbachia species, can manipulate the sexual development and reproduction of their insect hosts. For example, Wolbachia infection induces male-specific death in the Asian corn borer Ostrinia furnacalis by targeting the host factor Masculinizer (Masc), an essential protein for masculinization and dosage compensation in lepidopteran insects. Here we identify a Wolbachia protein, designated Oscar, which interacts with Masc via its ankyrin repeats. Embryonic expression of Oscar inhibits Masc-induced masculinization and leads to male killing in two lepidopteran insects, O. furnacalis and the silkworm Bombyx mori. Our study identifies a mechanism by which Wolbachia induce male killing of host progeny. |
| 巻・号 | 13(1) |
| ページ | 6764 |
| 公開日 | 2022-11-14 |
| DOI | 10.1038/s41467-022-34488-y |
| PII | 10.1038/s41467-022-34488-y |
| PMID | 36376299 |
| PMC | PMC9663696 |
| MeSH | Animals Bombyx* / genetics Bombyx* / metabolism Dosage Compensation, Genetic Insect Proteins / genetics Insect Proteins / metabolism Male Moths* / microbiology Wolbachia* / metabolism |
| IF | 12.121 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 41 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| カイコ | p50 |