論文 - 詳細
| RRC ID | 75209 |
|---|---|
| 著者 | Oikawa D, Yamashita S, Takahashi S, Waki T, Kikuchi K, Abe T, Katayama T, Nakayama T. |
| タイトル | (+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis. |
| ジャーナル | Biochem Biophys Res Commun |
| 巻・号 | 590 |
| ページ | 158-162 |
| 公開日 | 2022-1-29 |
| DOI | 10.1016/j.bbrc.2021.12.088 |
| PII | S0006-291X(21)01731-9 |
| PMID | 34974305 |
| MeSH | Benzodioxoles / chemistry Benzodioxoles / pharmacology Dioxoles / chemistry Dioxoles / pharmacology* Enzyme Inhibitors / pharmacology* Gastrointestinal Microbiome* / drug effects Kinetics Lignans / chemistry Lignans / pharmacology* Molecular Docking Simulation Phenols / chemistry Phenols / pharmacology Renal Insufficiency, Chronic / enzymology* Renal Insufficiency, Chronic / etiology* Sesamum / chemistry* Tryptophanase / antagonists & inhibitors* Tryptophanase / metabolism |
| リソース情報 | |
| 一般微生物 | JCM 5827 JCM 1658 JCM 1238 JCM 1672 JCM 1673 |