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  • Search Condition : Filter (MeSH = Enzyme Inhibitors / pharmacology*)
Species Resource Title
Human and Animal Cells MCF7(RCB1904) Identification of U83836E as a γ-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth.
Human and Animal Cells HCE-T(RCB2280) Identification of sulfonic acids as efficient ecto-5'-nucleotidase inhibitors.
Human and Animal Cells K562(RCB0027) Effect of a novel antibiotic, heliquinomycin, on DNA helicase and cell growth.
Human and Animal Cells MIA Paca2(RCB2094) Ribonucleotide reductase is an effective target to overcome gemcitabine resistance in gemcitabine-resistant pancreatic cancer cells with dual resistant factors.
Human and Animal Cells B16 , SK-MEL-28(RCB1930) WP1066, a small molecule inhibitor of the JAK/STAT3 pathway, inhibits ceramide glucosyltransferase activity.
Human and Animal Cells HF19(RCB0210) Synthesis, docking, cytotoxicity, and LTA4H inhibitory activity of new gingerol derivatives as potential colorectal cancer therapy.
Human and Animal Cells TGBC11TKB(RCB1148) Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Human and Animal Cells HOUA-I(RCB0659) EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis.
Human and Animal Cells HGC-27(RCB0500) Synthesis and antitumor activity of novel benzimidazole-5-carboxylic acid derivatives and their transition metal complexes as topoisomerease II inhibitors.
Human and Animal Cells Ba/F3(RCB0805) , IC-2(RCB0102) Suppression of apoptotic cell death of IL-3-dependent cell lines by ER/SR Ca2+-ATPase inhibitors upon IL-3 deprivation.
Human and Animal Cells ST2(RCB0224) Reciprocal control of expression of mRNAs for osteoclast differentiation factor and OPG in osteogenic stromal cells by genistein: evidence for the involvement of topoisomerase II in osteoclastogenesis.
Human and Animal Cells DT40(RCB1464) , SHP2^(-) DT40(RCB1502) NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
Human and Animal Cells GAKS(RCB1452) Naringenin suppresses Edwardsiella tarda infection in GAKS cells by NanA sialidase inhibition.
Human and Animal Cells WI-38(RCB0702) , HeLa Identification of small molecule inhibitors of human COQ7.
Human and Animal Cells ST2(RCB0224) FR177995, a novel vacuolar ATPase inhibitor, exerts not only an inhibitory effect on bone destruction but also anti-immunoinflammatory effects in adjuvant-induced arthritic rats.
Human and Animal Cells MH7A(RCB1512) Preparative separation of the flavonoid fractions from Periploca forrestii Schltr. ethanol extracts using macroporous resin combined with HPLC analysis and evaluation of their biological activities.
Human and Animal Cells HeLa(RCB0007) Identification of Small-Molecule Inhibitors of Human Golgi Mannosidase via a Drug Repositioning Screen.
Human and Animal Cells PC-3(RCB2145) , HL-60(RCB3683) , LNCap.FGC(RCB2144) Blockade of γ-Glutamylcyclotransferase Enhances Docetaxel Growth Inhibition of Prostate Cancer Cells.
Human and Animal Cells 293(RCB1637) Identification of ryuvidine as a KDM5A inhibitor.
Human and Animal Cells K562(RCB0027) , HL60 , Jurkat , RPMI8226(RCB3010) , Raji Molecular targeting of inosine-5'-monophosphate dehydrogenase by FF-10501 promotes erythropoiesis via ROS/MAPK pathway.