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  • Search Condition : Filter (MeSH = Enzyme Inhibitors / pharmacology*)
Species Resource
Human and Animal Cells Polyploidization of 2nH1 (ES) cells by K-252a and staurosporine.
Prokaryotes E. coli ME7828(YK1100) , ME7796(AZ5372) , JW3100(W3100) , ME8577(JC12334) Mutants suppressing novobiocin hypersensitivity of a mukB null mutation.
Human and Animal Cells K562 DNA topoisomerase II inhibitor, etoposide, induces p21WAF1/CIP1 through down-regulation of c-Myc in K562 cells.
Human and Animal Cells OS-RC-2 Prominent induction of cyclin B1 in G2/M renal cancer cells with butyrolactone 1.
Human and Animal Cells NB1RGB , MRC-5 Induction by staurosporine of hepatocyte growth factor production in human skin fibroblasts independent of protein kinase inhibition.
Human and Animal Cells MKN45 Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45.
Human and Animal Cells K562 Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation of K562 cells.
Human and Animal Cells K562 Inactivation of ERK accelerates erythroid differentiation of K562 cells induced by herbimycin A and STI571 while activation of MEK1 interferes with it.
Human and Animal Cells RAW 264 , RCN-9 Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development.
Human and Animal Cells RAW 264 6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages.
Prokaryotes E. coli ME9062 (BW25113 ) Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli.
Arabidopsis / Cultured plant cells, genes pda04357 AtHMA1 is a thapsigargin-sensitive Ca2+/heavy metal pump.
Mice B6.Cg-Tg(Tec-p210 BCR/ABL1)1Homy(RBRC02339) NADPH oxidases as therapeutic targets in chronic myelogenous leukemia.
DNA material Genome Network human cDNA clone IRAL015K15 (HGY086255) , IRAL037F09 (HGY094929) , IRAK022O02 (HGX009138) , IRAL007N16 (HGY083128) , IRAL016K22 (HGY086662) , IRAL005A23 (HGY082023) , IRAK004O20 (HGX001956) , IRAL006E09 (HGY082505) , IRAL004F23 (HGY081743) A practical fluorogenic substrate for high-throughput screening of glutathione S-transferase inhibitors.
Human and Animal Cells Discovery of a novel nicotinamide phosphoribosyl transferase (NAMPT) inhibitor via in silico screening.
Human and Animal Cells Structure-activity relationships of the thujaplicins for inhibition of human tyrosinase.
Human and Animal Cells Human CYP3A4-introduced HepG2 cells: in vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity.
Human and Animal Cells Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner.
Human and Animal Cells Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1.
Human and Animal Cells Suppressive effect of maslinic acid on PMA-induced protein kinase C in human B-lymphoblastoid cells.