| RRC ID |
75524
|
| Author |
Oku N, Takemura S, Onaka H, Igarashi Y.
|
| Title |
NMR characterization of streptogramin B and L-156,587, a non-synergistic pair of the streptogramin family antibiotic complexes produced inductively by a combined culture of Streptomyces albogriseolus and Tsukamurella pulmonis.
|
| Journal |
Magn Reson Chem
|
| Abstract |
The complete 1 H and 13 C NMR characterization of streptogramin B (1), the major component of a clinically important synergistic antibiotic complex, was presented for the first time, along with those of L-156,587 (2), a dehydrated congener of streptogramin A (3). Compounds 1 and 2 were not synergistic and produced by Streptomyces albogriseolus in co-culture with Tsukamurella pulmonis, which poses a question on the adaptive significance of the induced production of this antibiotic pair.
|
| Volume |
60(2)
|
| Pages |
261-270
|
| Published |
2022-2-1
|
| DOI |
10.1002/mrc.5219
|
| PMID |
34547830
|
| MeSH |
Actinobacteria
Anti-Bacterial Agents* / pharmacology
Streptogramin B*
Streptogramins
Streptomyces
Virginiamycin / analogs & derivatives
|
| Resource |
| General Microbes |
JCM 2499 |
