Reference - Detail
| RRC ID | 75524 |
|---|---|
| Author | Oku N, Takemura S, Onaka H, Igarashi Y. |
| Title | NMR characterization of streptogramin B and L-156,587, a non-synergistic pair of the streptogramin family antibiotic complexes produced inductively by a combined culture of Streptomyces albogriseolus and Tsukamurella pulmonis. |
| Journal | Magn Reson Chem |
| Abstract |
The complete 1 H and 13 C NMR characterization of streptogramin B (1), the major component of a clinically important synergistic antibiotic complex, was presented for the first time, along with those of L-156,587 (2), a dehydrated congener of streptogramin A (3). Compounds 1 and 2 were not synergistic and produced by Streptomyces albogriseolus in co-culture with Tsukamurella pulmonis, which poses a question on the adaptive significance of the induced production of this antibiotic pair. |
| Volume | 60(2) |
| Pages | 261-270 |
| Published | 2022-2-1 |
| DOI | 10.1002/mrc.5219 |
| PMID | 34547830 |
| MeSH | Actinobacteria Anti-Bacterial Agents* / pharmacology Streptogramin B* Streptogramins Streptomyces Virginiamycin / analogs & derivatives |
| Altmetric score |
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| General Microbes | JCM 2499 |