論文 - 詳細
| RRC ID | 75524 |
|---|---|
| 著者 | Oku N, Takemura S, Onaka H, Igarashi Y. |
| タイトル | NMR characterization of streptogramin B and L-156,587, a non-synergistic pair of the streptogramin family antibiotic complexes produced inductively by a combined culture of Streptomyces albogriseolus and Tsukamurella pulmonis. |
| ジャーナル | Magn Reson Chem |
| Abstract |
The complete 1 H and 13 C NMR characterization of streptogramin B (1), the major component of a clinically important synergistic antibiotic complex, was presented for the first time, along with those of L-156,587 (2), a dehydrated congener of streptogramin A (3). Compounds 1 and 2 were not synergistic and produced by Streptomyces albogriseolus in co-culture with Tsukamurella pulmonis, which poses a question on the adaptive significance of the induced production of this antibiotic pair. |
| 巻・号 | 60(2) |
| ページ | 261-270 |
| 公開日 | 2022-2-1 |
| DOI | 10.1002/mrc.5219 |
| PMID | 34547830 |
| MeSH | Actinobacteria Anti-Bacterial Agents* / pharmacology Streptogramin B* Streptogramins Streptomyces Virginiamycin / analogs & derivatives |
| リソース情報 | |
| 一般微生物 | JCM 2499 |