論文 - 詳細
RRC ID | 78572 |
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著者 | I. Bányász, I. Rajta, V. Havránek, A. Mackova, A. J. Laki, M. S. Z. Kellermayer, Z. Szittner, S. Kurunczi, Sz. Novák, I. Székács, R. Horváth, M. Fried, G. U. L. Nagy |
タイトル | Design, fabrication, and characterization of picowell arrays on cyclic olefin copolymer surfaces generated with a 10.5 MeV N4+ ion microbeam |
ジャーナル | Applied Physics Letters |
Abstract |
Handling of picoliter-to-nanoliter-scale volumes and objects has increasing importance in life sciences. This is the volume scale of cell extractions and individual living cells. Here, we introduce a method of generating a picoliter-scale device by direct writing of picowell arrays on a ZEONOR™ copolymer surface with high-energy medium-mass ion microbeam. Arrays of various microstructures were written in the sample using a microbeam of 10.5 MeV N4+ ions at various implanted ion fluences. The best array was obtained by implantation of annuli of 10 and 11 μm of inner and outer diameters with a fluence of 7.8 × 1012 ions/cm2. |
巻・号 | 123 |
公開日 | 2023-7-31 |
DOI | 10.1063/5.0155681 |
リソース情報 | |
ヒト・動物細胞 | HeLa/Fucci(RCB2812) |