論文 - 詳細
| RRC ID | 78863 |
|---|---|
| 著者 | Wiese C, Abele M, Al B, Altmann M, Steiner A, Kalbfuß N, Strohmayr A, Ravikumar R, Park CH, Brunschweiger B, Meng C, Facher E, Ehrhardt DW, Falter-Braun P, Wang ZY, Ludwig C, Assaad FF. |
| タイトル | Regulation of adaptive growth decisions via phosphorylation of the TRAPPII complex in Arabidopsis. |
| ジャーナル | J Cell Biol |
| Abstract |
Plants often adapt to adverse or stress conditions via differential growth. The trans-Golgi network (TGN) has been implicated in stress responses, but it is not clear in what capacity it mediates adaptive growth decisions. In this study, we assess the role of the TGN in stress responses by exploring the previously identified interactome of the Transport Protein Particle II (TRAPPII) complex required for TGN structure and function. We identified physical and genetic interactions between AtTRAPPII and shaggy-like kinases (GSK3/AtSKs) and provided in vitro and in vivo evidence that the TRAPPII phosphostatus mediates adaptive responses to abiotic cues. AtSKs are multifunctional kinases that integrate a broad range of signals. Similarly, the AtTRAPPII interactome is vast and considerably enriched in signaling components. An AtSK-TRAPPII interaction would integrate all levels of cellular organization and instruct the TGN, a central and highly discriminate cellular hub, as to how to mobilize and allocate resources to optimize growth and survival under limiting or adverse conditions. |
| 巻・号 | 223(5) |
| 公開日 | 2024-5-6 |
| DOI | 10.1083/jcb.202311125 |
| PII | 276670 |
| PMID | 38558238 |
| PMC | PMC10983811 |
| MeSH | Arabidopsis* / metabolism Arabidopsis Proteins* / genetics Arabidopsis Proteins* / metabolism Carrier Proteins* / metabolism Glycogen Synthase Kinase 3 / metabolism Phosphorylation Protein Transport trans-Golgi Network / metabolism |
| IF | 8.811 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 23 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| シロイヌナズナ / 植物培養細胞・遺伝子 | pda13397 pda08293 |