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  • 検索条件 : 絞込み (MeSH = Glycogen Synthase Kinase 3 / metabolism)
生物種 リソース名 タイトル
遺伝子材料 pFLAG-human yes-associated protein (YAP)1 (RDB13968) Differentiation-inducing factor-1 inhibits EMT by proteasomal degradation of TAZ and YAP in cervical and colon cancer cell lines.
ヒト・動物細胞 253G1(HPS0002) Yes-associated protein activation potentiates glycogen synthase kinase-3 inhibitor-induced proliferation of neonatal cardiomyocytes and iPS cell-derived cardiomyocytes.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) CRL2KLHDC3 and CRL1Fbxw7 cooperatively mediate c-Myc degradation.
シロイヌナズナ / 植物培養細胞・遺伝子 pda13397 , pda08293 Regulation of adaptive growth decisions via phosphorylation of the TRAPPII complex in Arabidopsis.
ショウジョウバエ DGRC#109027 Concurrent targeting of GSK3 and MEK as a therapeutic strategy to treat pancreatic ductal adenocarcinoma.
線虫 tm4146 Sperm-specific glycogen synthase kinase 3 is required for sperm motility and the post-fertilization signal for female meiosis II in Caenorhabditis elegans.
ヒト・動物細胞 MCF7(RCB1904) Differentiation-inducing factor-1 suppresses cyclin D1-induced cell proliferation of MCF-7 breast cancer cells by inhibiting S6K-mediated signal transducer and activator of transcription 3 synthesis.
ショウジョウバエ GL00367 Drosophila CLASP regulates microtubule orientation and dendrite pruning by suppressing Par-1 kinase.
ヒト・動物細胞 iPSC line Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells.
ショウジョウバエ Canton S Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling.
遺伝子材料 pCMFlag_hsNR5A1 (RDB06299) Overexpression of Nuclear Receptor 5A1 Induces and Maintains an Intermediate State of Conversion between Primed and Naive Pluripotency.
ヒト・動物細胞 Hep G2(RCB1886) , ATDC5(RCB0565) Molecular hydrogen suppresses activated Wnt/β-catenin signaling.
線虫 NA Progressive neurodegeneration in C. elegans model of tauopathy.
ヒト・動物細胞 9-15C(RCB2323) PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL.
ヒト・動物細胞 P19 Reelin signals survival through Src-family kinases that inactivate BAD activity.
ヒト・動物細胞 HeLa(RCB0007) , 293(RCB1637) Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic beta-catenin protein.
ヒト・動物細胞 MIA Paca2(RCB2094) Inhibition of glycogen synthase kinase-3 beta induces apoptosis and mitotic catastrophe by disrupting centrosome regulation in cancer cells.
ヒト・動物細胞 K562 Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
ショウジョウバエ DGRC#109861 , DGRC#109862 , DGRC#109864 Shaggy/glycogen synthase kinase 3β and phosphorylation of Sarah/regulator of calcineurin are essential for completion of Drosophila female meiosis.
ヒト・動物細胞 PC-12(RCB0009) Colchicine-induced apoptosis was prevented by glycogen synthase kinase-3 inhibitors in PC12 cells.