Reference - Detail
| RRC ID | 78966 |
|---|---|
| Author | Melvin Yong, Zhi Y. Kok, Chong H. Koh, Wenbin Zhong, Justin TY. Ng, Yuguang Mu, Mary B. Chan-Park, Yunn-Hwen Gan |
| Title | Membrane Potential-Dependent Uptake of Cationic Oligoimidazolium Mediates Bacterial DNA Damage and Death |
| Journal | Antimicrobial Agents and Chemotherapy |
| Abstract |
The treatment of bacterial infections is becoming increasingly challenging with the emergence of antimicrobial resistance. Thus, the development of antimicrobials with novel mechanisms of action is much needed. |
| Volume | 67 |
| Published | 2023-5-17 |
| DOI | 10.1128/aac.00355-23 |
| PMID | 37125913 |
| PMC | PMC10190574 |
| MeSH | Animals Anti-Bacterial Agents / pharmacology Anti-Infective Agents* Antimicrobial Cationic Peptides* / pharmacology Bacteria DNA, Bacterial Mammals Membrane Potentials Microbial Sensitivity Tests |
| IF | 4.904 |
| Resource | |
| Prokaryotes E. coli | JW3786-KC JW3596-KC |