RRC ID 83128
Author Mizuno-Iijima S, Kawamoto S, Asano M, Mashimo T, Wakana S, Nakamura K, Nishijima KI, Okamoto H, Saito K, Yoshina S, Miwa Y, Nakamura Y, Ohkuma M, Yoshiki A.
Title Mammalian genome research resources available from the National BioResource Project in Japan.
Journal Mamm Genome
Abstract Mammalian genome research has conventionally involved mice and rats as model organisms for humans. Given the recent advances in life science research, to understand complex and higher-order biological phenomena and to elucidate pathologies and develop therapies to promote human health and overcome diseases, it is necessary to utilize not only mice and rats but also other bioresources such as standardized genetic materials and appropriate cell lines in order to gain deeper molecular and cellular insights. The Japanese bioresource infrastructure program called the National BioResource Project (NBRP) systematically collects, preserves, controls the quality, and provides bioresources for use in life science research worldwide. In this review, based on information from a database of papers related to NBRP bioresources, we present the bioresources that have proved useful for mammalian genome research, including mice, rats, other animal resources; DNA-related materials; and human/animal cells and microbes.
Volume 35(4)
Pages 497-523
Published 2024-12-1
DOI 10.1007/s00335-024-10063-2
PII 10.1007/s00335-024-10063-2
PMID 39261329
PMC PMC11522087
MeSH Animals Databases, Genetic Genome* Genomics / methods Humans Japan Mammals* / genetics Mice Rats
IF 2.287
Resource
Rats W-Tg(CAG-GFP)184Ys (StrainID=525) LEW-Tg(CAG-EGFP)1Ys (StrainID=647) W-Tg(Thy1-COP4/YFP*)4Jfhy (StrainID=1072) LE-Tg(Gt(ROSA)26Sor-CAG-tdTomato)24Jfhy (StrainID=1139) LEW-Tg(Gt(ROSA)26Sor-luc)11Jmsk (StrainID=649) F344-Il2rgem1Iexas (StrainID=1295) F344-Il2rgem7Kyo (StrainID=1099) F344-Il2rgem2Kyo (StrainID=979) NER/Kyo (StrainID=26) GRY/Idr (StrainID=498)