RRC ID 83354
Author Itaya M, Fujita K, Kuroki A, Tsuge K.
Title Bottom-up genome assembly using the Bacillus subtilis genome vector.
Journal Nat Methods
Abstract We established a protocol to construct complete recombinant genomes from their small contiguous DNA pieces and obtained the genomes of mouse mitochondrion and rice chloroplast using a B. subtilis genome (BGM) vector. This method allows the design of any recombinant genomes, valuable not only for fundamental research in systems biology and synthetic biology but also for various applications in the life sciences.
Volume 5(1)
Pages 41-3
Published 2008-1-1
DOI 10.1038/nmeth1143
PII nmeth1143
PMID 18066072
MeSH Bacillus subtilis / genetics* Bacterial Proteins / genetics* DNA, Bacterial / genetics* Genetic Engineering / methods* Genetic Vectors / genetics* Genome, Bacterial / genetics* Recombinant Proteins / genetics*
IF 30.822
Resource
Prokaryotes B. subtilis MBP34 MBP35