論文 - 詳細
| RRC ID | 84053 |
|---|---|
| 著者 | Saito TT, Yamamoto K, Minami H, Tsujiue T. |
| タイトル | Caenorhabditis elegans brc-1 mutation increases the number of COSA-1 foci in him-8 and zim-2 mutants. |
| ジャーナル | MicroPubl Biol |
| Abstract |
Crossover designation factors such as COSA-1 are concentrated at the specific DNA double-strand break (DSB) sites to promote crossover formation. zim-1 mutants, which show defects in the homologous chromosome pairing of chromosomes II and III, increase the COSA-1 foci/normal bivalent state compared to the expected value. The excess designation was suppressed by an additional mutation in brc-1 in zim-1 mutants. We demonstrated that the number of COSA-1 foci in him-8 and zim-2 mutants, showing defects in the pairing of the X and V chromosomes, respectively, increased compared to the expected value, and brc-1 mutation accelerated the number of COSA-1 foci in oogenesis. |
| 巻・号 | 2024 |
| 公開日 | 2024-1-1 |
| DOI | 10.17912/micropub.biology.001077 |
| PMID | 39132054 |
| PMC | PMC11310775 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Bluesky |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 線虫 | tm1145 tm611 tm574 |