Reference - Detail
| RRC ID | 85237 |
|---|---|
| Author | Kato K, Kumazawa M, Nakajima Y, Suzuki T, Dohmae N, Shen JR, Ifuku K, Nagao R. |
| Title | Structure of a photosystem I supercomplex from Galdieria sulphuraria close to an ancestral red alga. |
| Journal | Sci Adv |
| Abstract |
Red algae exhibit unique photosynthetic adaptations, characterized by photosystem I (PSI) supercomplexes containing light-harvesting complexes (LHCs), forming PSI-LHCI supercomplexes. In this study, we solved the PSI-LHCI structure of Galdieria sulphuraria NIES-3638 at 2.19-angstrom resolution using cryo-electron microscopy, revealing a PSI monomer core associated with seven LHCI subunits. Structural analysis uncovered the absence of phylloquinones, the common secondary electron acceptor in PSI of photosynthetic organisms, suggesting adaptation to a benzoquinone-like molecule. Phylogenetic analysis suggests that G. sulphuraria retains traits characteristic of an ancestral red alga, including distinctive LHCI binding and interaction patterns. Variations in LHCI composition and interactions across red algae, particularly in red-lineage chlorophyll a/b-binding-like protein and red algal LHCs, highlight evolutionary divergence and specialization. These findings not only deepen our understanding of red algal PSI-LHCI diversification but also enable us to predict features of an ancestral red algal PSI-LHCI supercomplex, providing a framework to explore evolutionary adaptations from an ancestral red alga. |
| Volume | 11(20) |
| Pages | eadv7488 |
| Published | 2025-5-16 |
| DOI | 10.1126/sciadv.adv7488 |
| PMID | 40378202 |
| PMC | PMC12083527 |
| MeSH | Cryoelectron Microscopy Light-Harvesting Protein Complexes* / chemistry Light-Harvesting Protein Complexes* / metabolism Models, Molecular Photosynthesis Photosystem I Protein Complex* / chemistry Photosystem I Protein Complex* / metabolism Phylogeny Rhodophyta* / metabolism |
| IF | 13.117 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 22 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Algae | NIES-2137 NIES-3638 |