論文 - 詳細
| RRC ID | 86645 |
|---|---|
| 著者 | White B, Lux T, Rusholme-Pilcher R, Juhász A, Kaithakottil G, Duncan S, Simmonds J, Rees H, Wright J, Colmer J, Ward S, Joynson R, Coombes B, Irish N, Henderson S, Barker T, Chapman H, Catchpole L, Gharbi K, Bose U, Okada M, Handa H, Nasuda S, Shimizu KK, Gundlach H, Lang D, Naamati G, Legg EJ, Bharti AK, Colgrave ML, Haerty W, Uauy C, Swarbreck D, Borrill P, Poland JA, Krattinger SG, Stein N, Mayer KFX, Pozniak C, 10+ Wheat Genome Project, Spannagl M, Hall A. |
| タイトル | De novo annotation reveals transcriptomic complexity across the hexaploid wheat pan-genome. |
| ジャーナル | Nat Commun |
| Abstract |
Wheat is the most widely cultivated crop in the world, with over 215 million hectares grown annually. The 10+ Wheat Genomes Project recently sequenced and assembled to chromosome-level the genomes of nine wheat cultivars, uncovering genetic diversity and selection within the pan-genome of wheat. Here, we provide a wheat pan-transcriptome with de novo annotation and differential expression analysis for these wheat cultivars across multiple tissues. Using the de novo annotations we identify cultivar-specific genes and define the core and dispensable genomes. Expression analysis across cultivars and tissues reveals conservation in expression between a large core set of homeologous genes, in addition to widespread changes in subgenome homeolog expression bias between cultivars and cultivar-specific expression profiles. We utilise both the newly constructed gene-based wheat pan-genome and pan-transcriptome, demonstrating variation in the prolamin superfamily and immune-reactive proteins across cultivars. |
| 巻・号 | 16(1) |
| ページ | 8538 |
| 公開日 | 2025-10-6 |
| DOI | 10.1038/s41467-025-64046-1 |
| PII | 10.1038/s41467-025-64046-1 |
| PMID | 41053037 |
| PMC | PMC12501010 |
| MeSH | Chromosomes, Plant / genetics Gene Expression Profiling Gene Expression Regulation, Plant Genetic Variation Genome, Plant* / genetics Molecular Sequence Annotation Polyploidy* Transcriptome* / genetics Triticum* / genetics |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 62 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.2 |
| リソース情報 | |
| コムギ | LPGKU2305 LPGKU2271 |