論文 - 詳細
| RRC ID | 88312 |
|---|---|
| 著者 | Araya-Donoso R, Baty SM, Johnson JE, Lasku E, Taft JM, Fisher RE, Losos JB, Dolby GA, Kusumi K, Geneva AJ. |
| タイトル | Structural Rearrangements and Selection Promote Phenotypic Evolution in Anolis Lizards. |
| ジャーナル | Genome Biol Evol |
| Abstract |
The genomic characteristics of adaptively radiated groups could contribute to their high species number and ecological disparity, by increasing their evolutionary potential. Here, we explored the genomic variation of Anolis lizards, focusing on three species with distinct phenotypes: Anolis auratus, one of the species with the longest tail; Anolis frenatus, one of the largest species; and Anolis carolinensis, one of the species that inhabits the coldest environments. We assembled and annotated two new chromosome-level reference genomes for A. auratus and A. frenatus and compared them with the available genomes of A. carolinensis and Anolis sagrei. We evaluated the presence of structural rearrangements, quantified the density of repeat elements, and identified potential signatures of positive selection in coding and regulatory regions. We detected substantial rearrangements in scaffolds 1, 2, and 3 of A. frenatus different from the other species, in which the rearrangement breakpoints corresponded to hotspots of developmental genes. Further, we detected an accumulation of repeats around key developmental genes in anoles and phrynosomatid outgroups. Finally, coding sequences and regulatory regions of genes relevant to development and physiology showed variation that could be associated with the unique phenotypes of the analyzed species. Our results show examples of the hierarchical genomic variation within anoles that could provide the substrate that promoted phenotypic disparity and contributed to their adaptive radiation. |
| 巻・号 | 17(11) |
| 公開日 | 2025-10-27 |
| DOI | 10.1093/gbe/evaf196 |
| PII | 8303492 |
| PMID | 41140024 |
| PMC | PMC12596200 |
| MeSH | Animals Biological Evolution Evolution, Molecular* Female Gene Rearrangement Genetic Variation Genome Lizards* / genetics Phenotype Selection, Genetic* |
| IF | 3.462 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Bluesky |
| 各媒体での言及数の合計 | 23 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| GBIF | Reptile specimens of Kanagawa Prefectural Museum of Natural History Herpetological specimens of Okinawa Prefectural Museum & Art Museum Herpetological collection of National Museum of Nature and Science Herpetological (amphibian & reptile) specimens of Ryukyu University Museum (Fujukan) |