| RRC ID |
88693
|
| 著者 |
Chaplin AV, Pikina AP, Shcherbakova VA, Sokolova SR, Podoprigora IV, Das MS, Koshkin FA, Ilyina GA, Vasiliadis IA, Efimov BA.
|
| タイトル |
Parabacteroides absconsus sp. nov., isolated from feces of a child with atopic dermatitis.
|
| ジャーナル |
Arch Microbiol
|
| Abstract |
An obligate anaerobic, Gram-negative rod-shaped bacterial strain designated AD58T was isolated from the feces of a 3-year-old boy with atopic dermatitis. The closest species is Parabacteroides fecalis with 96.98% 16S rRNA gene identity. The average nucleotide identity value between AD58T and P. fecalis AGMB00274T is 85.0-85.4%. The circular genome sequence is 3.77 Mbp long with 43.5 mol% G + C content. The strain AD58T grows at 32-42 °C, its pH range for growth is 6.0-7.5. No growth is observed in the presence of 1% or higher NaCl concentrations. The major fatty acids are anteiso-C15: 0, iso-C15: 0, and summed feature 11 (iso-C17: 0 3-OH and/or C18: 2 DMA), and the predominant respiratory quinone is MK-9. Conditioned media from AD58T increased expression of IL-8 but decreased expression of TLR-4 in HT29 cells. Based on the described properties, we propose AD58T as the type strain of Parabacteroides absconsus sp. nov. (= VKM B-3630T = JCM 35468T).
|
| 巻・号 |
207(1)
|
| ページ |
25
|
| 公開日 |
2025-1-5
|
| DOI |
10.1007/s00203-024-04221-y
|
| PII |
10.1007/s00203-024-04221-y
|
| PMID |
39757252
|
| MeSH |
Bacterial Typing Techniques
Bacteroidetes / classification
Bacteroidetes / genetics
Bacteroidetes / isolation & purification
Base Composition*
Child, Preschool
DNA, Bacterial / genetics
Dermatitis, Atopic* / microbiology
Fatty Acids* / analysis
Feces* / microbiology
Genome, Bacterial
HT29 Cells
Humans
Male
Phylogeny*
RNA, Ribosomal, 16S* / genetics
Sequence Analysis, DNA
|
| リソース情報 |
| 一般微生物 |
JCM35468 |
